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Foot metatarsal injury, medically known as Metatarsalgia, is a condition in which the ball of your foot becomes inflamed or painful. It may develop when you participate in activities that involve jumping and running. Metatarsalgia may cause sharp, burning, or aching pain in the ball of your foot. The pain may worsen when you stand, walk, run, or flex your foot. The condition may also feel like you have a pebble in your shoes. Common causes may include intense training or activity, excess weight, poorly fitting shoes, stress fractures, and foot deformities.